About Palmer Lab

Our goal is to understand the neural activity contributing to perception and behaviour in the mammalian brain. Individual neurons are continuously bombarded with thousands of synaptic inputs which must integrate to generate an internal representation of the external environment. We investigate how the brain processes this sensory information by measuring the activity of neurons within the neocortex. In particular, we measure the activity of dendrites, which actively transform synaptic inputs into neuronal output. 

We use various techniques to record from neurons in vivo including two photon calcium imaging, somatic and dendritic patch-clamp recordings and optogenetics. Through our work, we not only aim to reveal how sensory information is received, transformed and modulated in neurons, but also how this processing of synaptic input contributes to the overall neural network activity underlying behaviour.

cortex neurons.JPG